Although the cause (or causes) of Alzheimer's disease (AD) remain unknown, certain
risk factors may increase an individual's chances of developing the disease. The
greatest risk factor for developing AD is simply age. An older person is much
more likely to develop AD than someone who is younger. For example, according
to one study, if you are between 65 and 74 years old, your likelihood of developing
AD is 1 out of 100. But if you are over age 85, your chances are greater than
25 out of 100.
Hereditary factors also play an important role in the development of Alzheimer's
disease. Repeated studies have shown that individuals with an affected relative
are at increased risk to develop AD compared to those without a positive family
history.
Many further potential risk factors are currently under investigation, including:
- female gender
- head injury associated with loss of consciousness
- exposure to environmental and occupational substances, such as aluminum
- alcohol and tobacco consumption
- the presence of Down syndrome
Interestingly, individuals who have a history of arthritis and anti-inflammatory
use, take estrogen, or have completed a minimum 9th grade education may have some
protection against the disease.